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Symptoms and causes of endometriosis

People with endometriosis can have different symptoms. The severity of symptoms is not related to the number or extent of endometriosis lesions a person has.

Different factors can cause endometriosis symptoms to get better or worse over time. For example, treatments, age and a person’s environment.

On this page, you’ll learn more about common symptoms of endometriosis and what may increase the likelihood of developing the condition.

Topics on this page

Common symptoms of endometriosis

Common symptoms of endometriosis include:

  • severe period pain
  • deep pain during or after sex
  • infertility
  • persistent pelvic pain
  • heavy periods.

Less common symptoms include:

  • bowel symptoms (e.g. bloating, constipation, diarrhoea or pain when doing a poo)
  • feeling very tired
  • back pain
  • sleep problems
  • headache
  • urinary symptoms (e.g. pain when weeing or blood in your wee)
  • allergies.

Endometriosis and menopause

Most women with endometriosis experience the same menopausal symptoms as women without endometriosis.

Endometriosis symptoms often improve after menopause due to the drop in oestrogen hormone levels.

But menopause is not a ‘cure’ for endometriosis. Some women continue to have symptoms after natural or medically induced menopause.

If you have endometriosis and are using menopausal hormone therapy (MHT) to manage menopausal symptoms, it’s recommended you use combined MHT rather than oestrogen-only MHT.

Endometriosis and persistent pelvic pain

Some women who have endometriosis also have persistent pelvic pain (PPP). PPP is pain in your pelvic area that’s felt most days and lasts for more than 6 months. If you have PPP, we have lots of information to help you understand the problem and manage your pain.

If your endometriosis symptoms stop you from doing day-to-day activities, for example, work, study or exercise, see your doctor. It’s also a good idea to see your doctor if your symptoms are getting worse or making you feel anxious or depressed.

Read Zoe’s story about living with chronic pain.

Causes of endometriosis

It’s not yet known exactly how and why some women develop endometriosis. It’s a complex disease that depends on oestrogen. But it may also be influenced by other factors.

Backwards (retrograde) menstruation

When you have a period, blood flows out of your vagina. But it can also flow backwards along your fallopian tubes into your pelvic area. Nearly all women experience this, but the blood (which contains endometrial cells) is usually absorbed or broken down in the body. In some women, the endometrial tissue starts to grow and form lesions.

Diagram of a uterus affected by endometriosis
Diagram of a uterus affected by endometriosis

Genetics

Genetics play an important role, but genetics don’t fully explain why some women develop endometriosis and others don’t.

How body systems work

Researchers are looking at different factors that might cause endometriosis. For example, how the immune and hormone systems interact.

Risk factors for endometriosis

We need more research to show that genetics increase the risk for endometriosis, and to identify the genes involved. Other risk factors may include:

  • having a low birth weight
  • getting your first period at an early age
  • having a low body weight
  • having short menstrual cycles.

Can you prevent endometriosis?

There is no known way to prevent endometriosis. We need more research to understand what actions might help to reduce the risk of developing the condition.

Endometriosis and other health conditions

Endometriosis may be associated with other health conditions, but we need more research to better understand this. It’s helpful to be aware of the links, but it doesn’t mean you’re likely to develop these conditions:

  • depression and anxiety
  • other chronic pain conditions, such as migraine
  • uterine fibroids (non-cancerous tumours that grow into the wall of the uterus).
  • adenomyosis (where tissue that normally lines the uterus grows into the muscle wall)
  • ovarian, breast, endometrial and thyroid cancer (although the risk is small)
  • autoimmune diseases, such as lupus, rheumatoid arthritis or inflammatory bowel disease
  • early menopause
  • cardiovascular disease.

This con­tent has been reviewed by a group of med­ical sub­ject mat­ter experts, in accor­dance with Jean Hailes pol­i­cy.

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Last updated: 
16 September 2025
 | 
Last reviewed: 
31 March 2025

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