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Uterine cancer (cancer of the uterus)

Learn about uterine cancer, including the symptoms, causes, how it’s diagnosed and treatment options.
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What is uterine cancer?

Uterine cancer occurs when abnormal cells grow in the lining or muscle of the uterus. It’s the most diagnosed gynaecological cancer in Australia, mainly affecting women aged over 50.

There are 2 main types of uterine cancer:

  • endometrial cancer – the cancer starts in the lining of the uterus
  • uterine sarcoma – a rare cancer that develops in the muscle or tissues of the uterus.

Symptoms of uterine cancer

The most common symptom of uterine cancer is unusual vaginal bleeding, particularly bleeding after menopause.

Other common symptoms include:

  • periods that are heavier than usual, or a change to your periods
  • bleeding in between periods
  • periods that continue without a break.

Less common symptoms include:

  • watery, smelly discharge
  • unexplained weight loss
  • discomfort or pain in your belly
  • painful sex
  • difficulty weeing.

Talk to your doctor if you are worried about any of these symptoms. They may not be due to cancer, but it’s important to check.

Causes of uterine cancer

The exact cause of uterine cancer is not known, but it may be associated with:

  • a family history of cancer
  • certain genetic conditions
  • endometrial hyperplasia – a condition where the lining of the uterus is thicker than normal)
  • other health factors.

How is uterine cancer diagnosed?

You can’t screen for uterine cancer, so it’s important to see your doctor if you notice any symptoms.

Your doctor will ask about your:

  • symptoms
  • medical history
  • family medical history.

They may do a physical examination to check your:

  • vulva, vagina and cervix
  • uterus and pelvis.

They might also ask you to do blood and urine (wee) tests.

If your results suggest you may have uterine cancer, your doctor will refer you to a gynaecological oncologist (a specialist in gynaecological cancers) straight away.

You may need more tests to diagnose uterine cancer. For example:

  • an internal ultrasound (via the vagina) to look at your ovaries and uterus
  • a procedure to take a sample of cells from your uterus lining
  • imaging tests – to check if cancer has spread outside your uterus.

Treatments for uterine cancer

Treatment for uterine cancer depends on the extent of the cancer. It may include:

  • surgery
  • radiotherapy
  • hormone therapy (usually in advanced stages)
  • chemotherapy
  • palliative treatment.

Some cancer treatments, such as chemotherapy and radiotherapy, can cause menopause.

When to see your doctor about uterine cancer

It’s important to see your doctor if you notice any symptoms of uterine cancer. As with many cancers, early detection leads to the best treatment outcomes.

More resources on uterine cancer

For more information about uterine cancer, visit the:

If you would like to speak to a nurse for general information and support, call Cancer Council on 13 11 20 (9 am to 5 pm, Monday to Friday).

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