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Reviewed
Key learnings
- PMDD is different from PMS. PMDD is a severe condition that causes intense emotional and psychological distress before your periods.
- Common symptoms include extreme or sudden mood changes, irritability and anxiety.
- Treatment options include medicines, a healthy lifestyle and cognitive behavioural therapy (CBT).
- See your doctor if symptoms of PMDD have a big impact on your daily life and wellbeing.
Key learnings
- PMDD is different from PMS. PMDD is a severe condition that causes intense emotional and psychological distress before your periods.
- Common symptoms include extreme or sudden mood changes, irritability and anxiety.
- Treatment options include medicines, a healthy lifestyle and cognitive behavioural therapy (CBT).
- See your doctor if symptoms of PMDD have a big impact on your daily life and wellbeing.
What is premenstrual dysphoric disorder (PMDD)?
PMDD causes severe emotional and psychological distress in the lead-up to your periods. This condition can negatively impact your work, relationships and quality of life.
How is PMDD different to PMS?
PMDD and PMS can seem similar, but PMDD symptoms are much more intense.
Symptoms of PMDD
PMDD symptoms start one to 2 weeks before your periods. Symptoms usually settle after your periods start.
Common symptoms include:
- extreme or sudden mood changes, such as suddenly feeling sad or tearful, or increased sensitivity to rejection
- irritability, anger or conflict with others
- feeling depressed, hopeless, worthless or guilty
- anxiety, tension, or feeling ‘on edge’.
Other symptoms include:
- reduced interest in activities such as work, school, friendships or hobbies
- trouble concentrating
- tiredness, low energy or easily fatigued
- marked change in appetite, such as overeating or craving certain foods
- feeling overwhelmed or out of control
- changes in sleep patterns
- physical symptoms, such as breast tenderness, joint and muscle pains, headaches, bloating or weight gain.
What causes PMDD?
The exact cause of PMDD isn’t known. Ongoing research suggests it may be linked to overlapping factors, including:
- brain sensitivity to hormone changes during the menstrual cycle
- genetic factors
- stress
- inflammation.
How is PMDD diagnosed?
PMDD is diagnosed based on your symptoms and how they affect you. You must have at least 5 symptoms, including one mood symptom, that happen the week before your periods. If these symptoms happen for at least 2 menstrual cycles, you’re likely to be diagnosed with PMDD.
PMDD is sometimes mistaken for other conditions, such as bipolar disorder. PMDD is officially recognised as a mental health condition.
If you think you might have PMDD, you can track your symptoms, how they affect you and what helps. Record this information across at least 2 menstrual cycles.
For a printable tracker, visit the International Association for Premenstrual Disorders (IAPMD) website.
Treatments for PMDD
Treatment for PMDD depends on your symptoms and how much they affect your daily life. You may need a combination of treatments.
The Pill can help regulate hormone levels and relieve symptoms.
Gonadotropin-releasing hormone (GnRH) medicine can be used to suppress oestrogen production and periods. This is used in cases where other medicines haven’t worked.
Antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), may be prescribed to ease symptoms of PMDD. They can be taken continuously or just in the 2 weeks before your periods start.
Anti-inflammatory medicines can help with physical symptoms, such as headaches and cramps.
A healthy lifestyle may help reduce PMDD symptoms. For example:
- try to reduce stress with relaxation techniques (e.g. meditation)
- do regular physical activity (e.g. aerobic exercise like swimming or cycling)
- eat a balanced diet
- reduce caffeine, alcohol and smoking.
Learn more about nutrition and healthy living.
You can try other ways to manage PMDD symptoms. For example, cognitive behavioural therapy (CBT).
Certain vitamin, mineral and herb supplements, such as calcium, chaste berry, vitamin D, vitamin B6 and magnesium, may help. But there is not enough evidence to support their use.
It’s important to tell your doctor if you take any supplements, as they can affect other medicines.
In severe cases of PMDD, where medicines haven’t worked, your doctor might recommend a hysterectomy and removal of both ovaries and fallopian tubes. This will cause medically induced menopause.
It’s important to understand the risks and benefits of this procedure before making a decision.
When to see your doctor
See your doctor if you have symptoms of PMDD that impact your quality of life, for example, your school, work, social and family life.
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Our review process
This information has been reviewed by clinical experts and is based on the latest evidence.
Our content review process ensures our health information is accurate, trustworthy, current and useful.
We regularly check our information to make sure it reflects the latest clinical guidelines and key findings from large, reliable studies.
Where possible, we focus on Australian research to make our information more relevant locally.
Experts play a key role in reviewing our content. Clinicians at Jean Hailes check information for accuracy and real‑world relevance. These include GPs, gynaecologists, endocrinologists, psychologists and allied health professionals.
We also work with partner organisations, independent specialists and people with lived experience to make sure our content reflects both expert knowledge and the experiences of the community.